Bromantane Review

Bromantane (brand name Ladasten) was originally developed as an immuno-stimulant drug in the laboratories and pharmaceutical companies of Russia. Soldiers and sportsmen in Russia have been using Bromantine since the late 1980’s. It is adamantane derivative and was originally developed to stimulate the immune system.


Product Description:

Bromantane is a stimulant and an anxiolytic at the same time. These two effects usually negate the effects of each other so the fact that Bromatane acts as a mental relaxant and a stimulant makes this drug unique.

Bromantane was also used to reduce recovery times after strong physical exertion. Although this drug soon fell out of use by the army, it still continued to be researched in areas such as sports medicine, because it was found to increase athletic performance. Bromantane is said to act really fast to increase motivation, alertness and overall mental energy.

This nootropic has also been proven to provide athletes with performance improvements. However, in 1996 this drug was listed in the IOC list of banned substances shortly upon learning that it is being used by several athletes to gain advantage over other athletes in the year’s Olympic Games.

This nootropic supplement is regarded to be a new nootropic with psychostimulatory effects. It is also regarded to be actoprotector. This means that they are synthetic adaptogens with a remarkable magnitude that can enhance physical performance.

General thoughts:


This nootropic supplement is usually used in Russia as a treatment for neurasthenia. This medical condition is marked by depressed mood, anxiety, irritability and fatigue.

The very beneficial side effect profile of this nootropic is one contributing to factor to its improvement in popularity as a potential substance. Bromantane is one of the few stimulating drugs which can be said to fit this definition because „true“ nootropic drugs do not carry any addictive potential.

This nootropic would theoretically decrease any fatigue that comes alongside long periods of mental exertion because of its effects as an actoprotector. This feature makes Bromantane a possible study help. This effect would be improved by Bromantane’s stimulating effect, which leads to improved concentration and motivation. However, this nootropic has not yet seen any official testing regarding its exact effects on cognition and cognitive health.

There are a variety of benefits that Bromantane can provide. This includes, but is not limited to some of the following:

  • Exhibit anxiolytic effects
  • Increases mental and physical endurance under stress
  • Enhances amounts of dopamine and serotonin neurotransmitter in the brain
  • Stimulation of the nervous system
  • Helps with liver detoxification
  • Decreases anxiety
  • Shown to help boost mood and motivation
  • Improves cognition and learning capability
  • Low to no potential for addiction
  • Boosts the immune system
  • Low toxicity
  • Stimulates euphoria
  • Enhances muscle mass and strength
  • Decreases overheating
  • Very few side-effects
  • Helps protect against hyperthermia

How It Works

Bromantane is known to exhibit qualities of both adaptogens and stimulants. However, the exact methods of action of this nootropic are not as well researched as other nootropic substances.

This nootropic works mainly by inhibiting the reuptake of both serotonin and dopamine in the brain. Although the method of action is not that well understood, experimentation has indicated that the administration of Bromantane induces a release of dopamine.

Additionally, this nootropic also triggers a notable increase in the 5-HT and 5-HIAA content in the frontal cortex of the brain. It also delays an increase in their content in subcortial brain regions, therefore a stable reduction in the 5-HT and 5-HIAA in the cerebellum is noticed.

This increase activates the part of the brain that is responsible for short-term memory task, motivation, attention and reward.

Bromantane stimulates synthesis of cytochrome P-450, strengthens GABA-ergic mediation reducing gene expression and acts as an anxiolytic.

Bromantane Dosage

A typical single dosage of Bromantane can range from 50 to 100 mg. However, Bromantane dose seems to be sex-dependent.

Females absorb this drug much faster than males. That’s why this nootropic has a much shorter half-life in females than in males.

Time to achievement of this nootropic is 4 hours in males and 2.75 hours in females.  Bromantane is highly lipophilic and it is quickly absorbed by the gastrointestinal tract into the blood when taken orally.

The effective dosage for this nootropic supplement is 30 mg/kg in mice because Bromantane has a stimulant effect at this dosage.

In animal researches, toxicity was reached only at very high levels of administration (600 mg/kg in mice). This nootropic has a tranquilizing effect at toxic dosages.



Bromantane can be taken on its own but also does very well in nootropic stacks for synergistic benefits.

Bromantane, Kava Kava, AcetylCarnitine, Agmatine and Fish Oil Stack

Stacking Bromantane with Kava Kava,, AcetylCarnitine, Agmatine and Fish Oil would be a potent stack which would decrease anxiety, improve health, stimulation and motivation.

Bromantane, Clomipramine, Citalopram, Liothyronine (T3) and Agomelatine Stack

This is a very powerful stack that would to get you out of bed and not have to worry about falling asleep before noon.


If you would like to purchase Bromantane, here are the top brands:

  • Anonymous Pharm
  • Ladasten
  • Nootropica Bromantane Powder

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Side Effects:

There are no established side effects in the scientific literature surrounding this nootropic supplement. Bromantane has not demonstrated addictive potential, unlike most stimulant drugs and after prolonged periods of use it does not seem to build a tolerance.

One research suggests that high dosages of this supplement in rats can cause enhancement in the DNA-binding activity of the beta-amyloid precursor protein (β-APP) gene promoter.

This can be linked to the pathogenesis of Alzheimer’s disease. However, it is important to note that the dosages used in this research are around 68 times the normal prescription dosage of this nootropic.

Also, many users say that they wouldn’t recommend Bromantane for daily use because it made them feel light headed and out of it for some time.


Bromantane is available in both capsule and powder form. It is recommended to buy it in powder form because it may be cheaper. You can order Bromantane powder at or If you want to purchase the original Russian brand Ladasten, you can order it at

Bromantane is a nootropic supplement that provides the potential of numerous cognitive benefits. This nootropic works as a stimulant and anxiolytic simultaneously and for this reason it is considered to be a unique drug.

Bromantane also serves to boost performance by improving the body’s resistance to physical and mental fatigue and exhaustion. Unfortunately, this nootropic lacks the wide spectrum of study. However, it appears that there is relatively no risk for addiction when taking this drug.

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